Fmoc-Cys(Acm)-OH [86060-81-3] HEADING_TITLE

N-Fmoc-S-acetamido-L-cysteine

Catalog #: AFC106 CAS #: 86060-81-3
Formula: C21H22N2O5S M.W.: 414.5

Fmoc-Cys(Acm)-OH

 

 

 

 

 

 

 

Fmoc-Cys(Acm)-OH is often utilized in preparing peptides containing disulfide bridges.  The Acm protecting group can be removed and the disulfide bond formed simultaneously using iodine (C. G. Joseph, et al., J. Med. Chem., 2004, 47, 6702-10).  This deprotection/cyclization can be performed on resin (Technical Support Bulletin 1180).  The Acm group can also be removed without disulfide bond formation by using Hg(OAc)2 (E. de Oliveira, et al., Bioconjugate Chem., 2003, 14, 144-52).  Acm deprotection protocols are available in Technical Support Bulletin 1123.

Products Similar to Fmoc-Cys(Acm)-OH

Cat. # Product Cat. # Product
AFC105 Fmoc-Cys(Trt)-OH ABC106 Boc-Cys(Acm)-OH
AFC102 Fmoc-Cys(Bzl)-OH ABC110 Boc-Cys(Bzl)-OH
AFC120 Fmoc-Cys(tBu)-OH ABC115 Boc-Cys(pMeBzl)-OH
AFC125 Fmoc-Cys(pMeBzl)-OH ABC114 Boc-Cys(Mob)-OH
AFC110 Fmoc-Cys(Mmt)-OH ABC112 Boc-Cys(tBu)-OH
AFC125 Fmoc-Cys(Mob)-OH ABC113 Boc-Cys(Trt)-OH
AFC205 Fmoc-D-Cys(Trt)-OH ABC213 Boc-D-Cys(Trt)-OH
AFC206 Fmoc-D-Cys(Acm)-OH ABC125 Boc-Cys(Acm)-ONp
AFC196 Fmoc-Cys(Acm)-OPfp UBC152 Boc-Pen(pMeBzl)-OH
AFC195 Fmoc-Cys(Trt)-OPfp UBC115 Boc-Thz-OH
AFC295 Fmoc-D-Cys(Trt)-OPfp UBC252 Boc-D-Pen(pMeBzl)-OH
UFC172 Fmoc-Pen(Trt)-OH UBC215 Boc-D-Thz-OH
UFC272 Fmoc-D-Pen(Trt)-OH AZC110 Z-Cys(Mob)-OH
UFC115 Fmoc-Thz-OH AZC105 Z-Cys(Z)-OH
MFC105 Fmoc-MeCys(Trt)-OH  

MSDS