Fmoc-D-Cys(Acm)-OH [168300-88-7] HEADING_TITLE

N-Fmoc-S-aceamido-D-cysteine

Catalog #: AFC206 CAS #:168300-88-7
Formula: C21H22N2O5S M.W.: 414.5

Fmoc-D-Cys(Acm)-OH

 

 

 

 

 

 

 

Fmoc-D-Cys(Acm)-OH was utilized to prepare cyclic opioid peptide antagonists (Y. Lu, et al., J. Med. Chem., 2006, 49, 5382-5).  It was also used in the preparation of a nuclease-resistant IRS1 siNRA conjugated to a disufide-bridged D-peptide analog of insulin-like growth factor.  The conjugatew was effective in knocking down expression of IRS-1 in breast cancer cells (G. Cesarone, et al., Bioconjugate Chem., 2007, 18, 1831-40).  Fmoc-D-Cys(Acm)-OH was also utilized to prepare a 111In-labeled PNA-disuulfide bridged D-peptide conjugate for imaging human pancreatic cancer (N. V. Amirkhanov, et al., Bioconjugate Chem., 2010, 21, 731-40).  

Products Similar to Fmoc-D-Cys(Acm)-OH

Cat. # Product Cat. # Product
AFC106 Fmoc-Cys(Acm)-OH ABC213 Boc-D-Cys(Trt)-OH
AFC205 Fmoc-D-Cys(Trt)-OH ABC106 Boc-Cys(Acm)-OH
AFC105 Fmoc-Cys(Trt)-OH ABC110 Boc-Cys(Bzl)-OH
AFC102 Fmoc-Cys(Bzl)-OH ABC115 Boc-Cys(pMeBzl)-OH
AFC120 Fmoc-Cys(tBu)-OH ABC114 Boc-Cys(Mob)-OH
AFC125 Fmoc-Cys(pMeBzl)-OH ABC112 Boc-Cys(tBu)-OH
AFC110 Fmoc-Cys(Mmt)-OH ABC113 Boc-Cys(Trt)-OH
AFC125 Fmoc-Cys(Mob)-OH ABC125 Boc-Cys(Acm)-ONp
AFC196 Fmoc-Cys(Acm)-OPfp UBC152 Boc-Pen(pMeBzl)-OH
AFC195 Fmoc-Cys(Trt)-OPfp UBC115 Boc-Thz-OH
AFC295 Fmoc-D-Cys(Trt)-OPfp UBC252 Boc-D-Pen(pMeBzl)-OH
UFC172 Fmoc-Pen(Trt)-OH UBC215 Boc-D-Thz-OH
UFC272 Fmoc-D-Pen(Trt)-OH AZC110 Z-Cys(Mob)-OH
UFC115 Fmoc-Thz-OH AZC105 Z-Cys(Z)-OH
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