Fmoc-Phe(3-Cl)-OH [198560-44-0] HEADING_TITLE

N-Fmoc-3-chloro-L-phenylalanine

Other Names: Fmoc-Phe(m-Cl)-OH; Fmoc-meta-chlorophenylalanine

Catalog Number: UFF113 CAS Number: 198560-44-0
Formula: C24H20ClNO4 M.W.: 421.9

Fmoc-Phe(3-Cl)-OH

 

 

 

 

 

 

 

 

 

Fmoc-Phe(3-Cl)-OH is utilized to incorporate 3-chlorophenylalanine into peptides for SAR studies.  Phe(3-Cl) residues can undergo ruthenium-activated SNAr reations to produce a variety of 3-aryl products (CW West, DH Rich, Org. Lett., 1999, 1, 1819-22).

Chlorinated Phenylalanines

Cat. # Product Cat. # Product Cat. # Product
UHF112 H-Phe(2-Cl)-OH UBF112 Boc-Phe(2-Cl)-OH UFF112 Fmoc-Phe(2-Cl)-OH
UHF212 H-D-Phe(2-Cl)-OH UBF212 Boc-D-Phe(2-Cl)-OH UFF212 Fmoc-D-Phe(2-Cl)-OH
UHF113 H-Phe(3-Cl)-OH HCl UBF113 Boc-Phe(3-Cl)-OH UFF113 Fmoc-Phe(3-Cl)-OH
UHF213 H-D-Phe(3-Cl)-OH UBF213 Boc-D-Phe(3-Cl)-OH UFF213 Fmoc-D-Phe(3-Cl)-OH
UHF114 H-Phe(4-Cl)-OH UBF114 Boc-Phe(4-Cl)-OH UFF114 Fmoc-Phe(4-Cl)-OH
UHF214 H-D-Phe(4-Cl)-OH UBF214 Boc-D-Phe(4-Cl)-OH UFF214 Fmoc-D-Phe(4-Cl)-OH
UHF136 H-Phe(2,4-diCl)-OH UBF136 Boc-Phe(2,4-diCl)-OH UFF136 Fmoc-Phe(2,4-diCl)-OH
UHF236 H-D-Phe(2,4-diCl)-OH UBF236 Boc-D-Phe(2,4-diCl)-OH UFF236 Fmoc-D-Phe(2,4-diCl)-OH
UHF116 H-Phe(3,4-diCl)-OH UBF116 Boc-Phe(3,4-diCl)-OH UFF116 Fmoc-Phe(3,4-diCl)-OH
UHF216 H-D-Phe(3,4-diCl)-OH UBF216 Boc-D-Phe(3,4-diCl)-OH UFF216 Fmoc-D-Phe(3,4-diCl)-OH

3-Substituted Phenylalanines

H-Phe(3-Br)-OH   Boc-Phe(3-Br)-OH   Fmoc-Phe(3-Br)-OH
H-D-Phe(3-Br)-OH   Boc-D-Phe(3-Br)-OH   Fmoc-D-Phe(3-Br)-OH
H-Phe(3-Cl)-OH   Boc-Phe(3-Cl)-OH   Fmoc-Phe(3-Cl)-OH
H-D-Phe(3-Cl)-OH   Boc-D-Phe(3-Cl)-OH   Fmoc-D-Phe(3-Cl)-OH
H-Phe(3-F)-OH   Boc-Phe(3-F)-OH   Fmoc-Phe(3-F)-OH
H-D-Phe(3-F)-OH    Boc-D-Phe(3-F)-OH   Fmoc-D-Phe(3-F)-OH
H-Phe(3-CN)-OH   Boc-Phe(3-CN)-OH   Fmoc-Phe(3-CN)-OH
H-D-Phe(3-CN)-OH   Boc-D-Phe(3-CN)-OH   Fmoc-D-Phe(3-CN)-OH
H-Phe(3-Me)-OH   Boc-Phe(3-Me)-OH   Fmoc-Phe(3-Me)-OH
H-D-Phe(3-Me)-OH   Boc-D-Phe(3-Me)-OH   Fmoc-D-Phe(3-Me)-OH
H-Phe(3-CF3)-OH   Boc-Phe(3-CF3)-OH   Fmoc-Phe(3-CF3)-OH
H-D-Phe(3-CF3)-OH   Boc-D-Phe(3-CF3)-OH   Fmoc-D-Phe(3-CF3)-OH

MSDS