HOOBt [28230-32-2] HEADING_TITLE

3-Hydroxy,1,2,3-benzotriazin-4(3H)-one

Other Names: Hydroxy-3,4-dihydro-4-oxo-1,2,3-benzotriazine

Catalog Number: CXZ015 CAS Number: 28230-32-2
Formula: C7H5N3O2 M.W.: 163.1

HOOBt

 

 

 

 

HOOBt is utilized with carbodiimide reagents to form activated HOOBt esters of protected amino acids for coupling.  The -OOBt anion, formed when the activated amino acid ester couples with the N-temninal amino acid of the peptide chain, produces a yellow color in the coupling reaction mixture.  The extent of the coupling reaction may be estimated by the intesity of the yellow color.

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MSDS