HOBt hydrate [123333-53-9] HEADING_TITLE

1-Hydroxybenzotriazole hydrate

Other Names: HOBt H2O

Catalog #: CXZ010 CAS #: 123333-53-9
Formula: C6H7N3O2 M.W.: 153.1

HOBt hydrate

 

 

 

 

HOBt hydrate is utilized in solid phase peptide synthesis as an additive during amino acid activation and coupling to suppress racemization.  It is reported that adding a small amount of HOBt to the Fmoc cleavage solution can suppress aspartimide formation.  (T. Michels, et al., Org. Lett., 2012, 14, 5218-21)  Anhydrous HOBt poses a risk of explosion, but HOBt hydrate is desensitized.

Products Similar to HOBt hydrate

Cat. # Product
CXZ021 Oxyma
CXZ012 HOAt
CXZ096 6-Cl-HOBt
CXZ015 HOOBt
CXZ022 HOSu
   

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