PyBOP [128625-52-5] HEADING_TITLE

(Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate

Catalog #: CXZ050 CAS #: 128625-52-5
Formula: C18H28F6N6OP2 M.W.: 520.39

PyBOP

 

 

 

 

 

 

 

 

PyBOP is an in situ coupling reagent utilized in solid phase peptide synthesis.  PyBOP may be utilized in place of BOP without loss of yield or efficiency.  PyBOP is also utilized in head-to-tail cyclizations and fragment condesation reactions.  In on-resin cyclization of cyclohexapeptidesand above, PyBOP produces essentially quantitative yields (A Thakkar, TB Trinh, D Pei, ACS Comb. Sci., 2013, 15, 120-9).

PyBOP Physical Properties

Assay: 98%

White to light yellow powder

Mp: 154-156 °C (dec)(lit)

Storage temp: 2-8 °C

Solubility: 1 mmol in 2 mL DMF

Other Products Related to PyBOP

Cat. # Product Cat. # Product
CXZ001 BOP CXZ090 BOP-Cl
CXZ002 CDI CXZ031 COMU
CXZ003 DCC CXZ004 DIC
CXZ060 DEPBT CXZ009 DSC
CXZ005 EDC HCl CXZ025 HATU
CXZ020 HBTU CXZ030 HCTU
CXZ012 HOAt CXZ010 HOBt H2O
CXZ096 6-Cl-HOBt CXZ015 HOOBt
CXZ022 HOSu CXZ021 Oxyma
CXZ070 PyAOP CXZ055 PyBrOP
CXZ045 TATU CXZ040 TBTU
CXZ042 TCFH CXZ065 TDBTU
CXZ043 TNTU CXZ044 TOTU
CXZ046 TPTU CXZ041 TSTU

MSDS