DEPBT [165534-43-0] HEADING_TITLE

3-(Diethoxyphosphoryloxy)-1,2,3-benzotriazin-4(3H)-one

Catalog #: CXZ060 CAS #: 165534-43-0
Formula: C11H14N3O5P M.W.: 299.22

DEPBT

 

 

 

 

 

DEPBT causes very little racemization and the hydroxy groups of Tyr, Ser and Thr sidechains and the imidazole ring of His sidechains do not require protection when DEPBT is utilized as a coupling reagent (YH Ye, H Li, X Jiang, Biopolymers, 2005, 80, 172-8).  It is especially useful for coupling easily racemized residues such as arylglycines.  It is also utilized in head-to-tail cyclization of linear peptides (M Liu, et al., J. Pept. Res., 2005, 65, 55-64) and to couple glycosylamines to Asp and Glu residues (R Chen, TJ Tolbert, J. Am. Che. Soc., 2010, 132, 3211-6).

DEPBT Physical Properties

Assay: 98+%

White to Light yellow powder

Mp: 72-75 °C

Storage temp: 2-8 °C

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Cat. # Product Cat. # Product
CXZ001 BOP CXZ090 BOP-Cl
CXZ002 CDI CXZ031 COMU
CXZ003 DCC CXZ004 DIC
CXZ009 DSC CXZ005 EDC
CXZ025 HATU CXZ020 HBTU
CXZ030 HCTU CXZ012 HOAt
CXZ010 HOBt H2O CXZ096 6-Cl-HOBt
CXZ015 HOOBt CXZ022 HOSu
CXZ021 Oxyma CXZ070 PyAOP
CXZ050 PyBOP CXZ055 PyBrOP
CXZ045 TATU CXZ040 TBTU
CXZ042 TCFH CXZ065 TDBTU
CXZ043 TNTU CXZ044 TOTU
CXZ046 TPTU CXZ041 TSTU

MSDS