Boc-Thr(Bzl)-OH [15260-10-3] HEADING_TITLE

N-Boc-O-benzyl-L-threonine

Other Names: Boc-L-Thr(Bzl)-OH

Catalog #: ABT110 CAS #: 15260-10-3
Formula: C16H23NO5 M.W.: 309.4

Boc-Thr(Bzl)-OH

 

 

 

 

 

Boc-Thr(Bzl)-OH is the threonine derivative commonly utilized in Boc SPPS.  The benzyl group is usually removed with HF, TFMSA or TMSOTf when the peptide is cleaved from the resin.  It can also be removed by hydrogenolysis.  Like isoleucine, threonine has a second chiral center.  The S,R-enantiomer is the naturally occuring form.  The S,S-enantiomer is allo-threonine. The threonine sidechain is a hydrogen bond donor and acceptor, thus it may be important in receptor binding and protein folding. Some threonine residues may play a role in regulation by being glycosylated or phosphorylated.

Products Similar to Boc-Thr(Bzl)-OH

Cat. # Product Cat. # Product
ABT210 Boc-D-Thr(Bzl)-OH AFT105 Fmoc-Thr(tBu)-OH
ABT120 Boc-Thr(tBu)-OH AFT205 Fmoc-D-Thr(tBu)-OH
ABT101 Boc-Thr-OH AFT135 Fmoc-allo-Thr(tBu)-OH
ABT105 Boc-Thr-OMe AFT235 Fmoc-D-allo-Thr(TBu)-OH
ABT115 Boc-Thr-OSu AFT192 Fmoc-Thr(tBu)-OPfp
ABT201 Boc-D-Thr-OH AFT106 Fmoc-Thr(Bzl)-OH
UBT112 Boc-beta-HThr(Bzl)-OH AFT107 Fmoc-Thr(Et)-OH
DBT105 Boc-Threoninol(Bzl) AFT101 Fmoc-Thr-OH
DBT205 Boc-D-Threoninol(Bzl) AFT103 Fmoc-Thr-OPac
ABS110 Boc-Ser(Bzl)-OH AFT201 Fmoc-D-Thr-OH
ABS210 Boc-D-Ser(Bzl)-OH MFT105 Fmoc-MeThr(tBu)-OH
UBS111 Boc-HSer(Bzl)-OH DFT105 Fmoc-Threoninol(tBu)
AZT101 Z-Thr-OH DFT101 Fmoc-Threoninol
AZT103 Z-Thr-NH2 DFT201 Fmoc-D-Threoninol
AZT105 Z-Thr-OBzl AFS105 Fmoc-Ser(tBu)-OH
AZT201 Z-D-Thr-OH AFS205 Fmoc-D-Ser(tBu)-OH
AFS106 Fmoc-Ser(Trt)-OH
UFS110 Fmoc-HSer(Trt)-OH

MSDS