Boc-His(Dnp)-OH IPA [25024-53-7] HEADING_TITLE

Nalpha-Boc-Nim-(2,4-dinitrophenyl)-L-histidine isopropyl alcohol solvate

Other Names: Boc-L-His(Dnp)-OH IPA

Catalog #: ABH110 CAS #: 25024-53-7
Formula: C17H19N5O8 · C3H8O M.W.: 481.5









Boc-His(Dnp)-OH is one of the histidine derivative often utilized in Boc SPPS.  It forms a stable slovate with isopropyl alcohol.  The Dnp group is not removed under acidic conditions, but is removed with nucleophiles such as thiophenol.  The Dnp containing byproducts formed when the protecting group is removed are highly colored and can cause the crude peptide to be yellow to orange.  Usually the Dnp group is removed before the peptide is cleaved from the resin.  This allows the highly colored byproducts to be easily separated from the peptide.

Products Similar to Boc-His(Dnp)-OH IPA

Cat. # Product Cat. # Product
ABH101 Boc-His-OH AFH105 Fmoc-His(Trt)-OH
ABH126 Boc-His(Boc)-OH AFH115 Fmoc-His(Fmoc)-OH
ABF130 Boc-His(Bom)-OH AFH110 Fmoc-His(Mmt)-OH
ABF115 Boc-His(Tos)-OH AFH195 Fmoc-His(Trt)-OPfp
ABH135 Boc-His(Trt)-OH AFH205 Fmoc-D-His(Trt)-OH
ABH140 Boc-His(Z)-OH MFH105 Fmoc-MeHis(Trt)-OH
ABH210 Boc-D-His(Dnp)-OH IPA UFH121 Fmoc-Ala(4-Thiazolyl)-OH
ABH230 Boc-D-His(Bom)-OH UFH221 Fmoc-D-Ala(4-Thiazolyl)-OH
ABH215 Boc-D-His(Tos)-OH AZH101 Z-His-OH
DBH105 Boc-Histidinol(Tos) AZH102 Z-His(Dnp)-OH
UBH121 Boc-Ala(4-Thiazolyl)-OH AZH201 Z-D-His-OH
UBH221 Boc-D-Ala(4-Thiazolyl)-OH