Boc-Gln(Xan)-OH [55260-24-7] HEADING_TITLE

Nalpha-Ndelta-xanthyl-L-glutamine

Other Names: Boc-L-Gln(Xan)-OH

Catalog #: ABQ110  CAS #: 55260-24-7
Formula: C23H26N2O6 M.W.: 426.5

Boc-Gln(Xan)-OH

 

 

 

 

 

Boc-Gln(Xan)-OH is a glutamine derivative often utilized in Boc SPPS.  The xanthyl protecting group improves the solubility of the glutamine derivative and protects the amide group from dehydration during dicarbodiimide activation.  The xanthyl group is removed under acidic conditions.  When the Boc group is removed for the next coupling, the xanthyl group is also removed.  Since the sidechain protection is mainly required during activation and coupling of the glutamine residue, removal of the xanthyl group after the glutamine residue is coupled to the peptide is not improtant.  The dehydration side reaction can be prevented by preactivating the amino acids or by utilizing activating reagents other than carbodiimides.

Products Similar to Boc-Gln(Xan)-OH

Catalog # Product Catalog # Product
ABQ105 Boc-Gln(Trt)-OH AFQ105 Fmoc-Gln(Trt)-OH
ABQ101 Boc-Gln-OH AFQ101 Fmoc-Gln-OH
ABQ115 Boc-Gln-ONp AFQ195 Fmoc-Gln(Trt)-OPfp
ABQ205 Boc-D-Gln(Trt)-OH AFQ191 Fmoc-Gln-OPfp
ABN105 Boc-Asn(Trt)-OH AFQ205 Fmoc-D-Gln(Trt)-OH
ABN110 Boc-Asn(Xan)-OH AFQ201 Fmoc-D-Gln-OH
ABN101 Boc-Asn-OH AFQ291 Fmoc-D-Gln-OPfp
ABN102 Boc-Asn-ONp AFN105 Fmoc-Asn(Trt)-OH
ABN201 Boc-D-Asn-OH AFN101 Fmoc-Asn-OH
UBQ101 Boc-beta-HGln-OH AFN195 Fmoc-Asn(Trt)-OPfp
UBN101 Boc-beta-HAsn-OH

AFN191

Fmoc-Asn-OPfp
AZQ105 Z-Gln(Trt)-OH AFN205 Fmoc-D-Asn(Trt)-OH
AZQ101 Z-Gln-OH AFN201 Fmoc-D-Asn-OH
AZN101 Z-Asn-OH UFQ111 Fmoc-beta-HGln(Trt)-OH
    UFQ101 Fmoc-beta-HGln-OH
    UFN101 Fmoc-beta-HAsn(Trt)-OH
    UFN102 Fmoc-beta-HAsn-OH

MSDS