Boc-Asn(Xan)-OH [65420-40-8] HEADING_TITLE

Nalpha-Boc-Ngamma-xanthyl-L-asparagine

Other Names: Boc-L-Asn(Xan)-OH

Catalog #: ABN110 CAS #: 65420-40-8
Formula: C22H24N2O6 M.W.: 412.4

Boc-Asn(Xan)-OH

 

 

 

 

 

Boc-Asn(Xan)-OH is the asparagine derivitive often utilized in Boc-SPPS.  The xanthyl protecting group on the side chain improves the solubility of the asparagine derivative and protects the amide group from dehydration during activation with carbodiimide reagents.  The xanthyl protecting group is removed with trifluoroacetic acid (TFA) during Boc deprotection.  Since the side chain protecting group is needed mostly during activation and coupling of the asparagine residue, its removal during subsquent Boc removal is not a significant problem.  The dehydration side reaction can be avoided by preactivating the amino acid derivatives before coupling or by utilizing activating reagents other than carbodiimides.

Products Similar to Boc-Asn(Xan)-OH

Cat. # Product Cat. # Product
ABN105 Boc-Asn(Trt)-OH AFN105 Fmoc-Asn(Trt)-OH
ABN101 Boc-Asn-OH AFN101 Fmoc-Asn-OH
ABN102 Boc-Asn-ONp AFN195 Fmoc-Asn(Trt)-OPfp
ABN201 Boc-D-Asn-OH AFN191 Fmoc-Asn-OPfp
ABQ105 Boc-Gln(Trt)-OH AFN205 Fmoc-D-Asn(Trt)-OH
ABQ110 Boc-Gln(Xan)-OH AFN201 Fmoc-D-Asn-OH
ABQ101 Boc-Gln-OH AFQ105 Fmoc-Gln(Trt)-OH
ABQ115 Boc-Gln-ONp AFQ101 Fmoc-Gln-OH
ABQ205 Boc-D-Gln(Trt)-OH AFQ195 Fmoc-Gln(Trt)-OPfp
UBN101 Boc-beta-HAsn-OH AFQ191 Fmoc-Gln-OPfp
UBQ101 Boc-beta-HGln-OH AFQ205 Fmoc-D-Gln(Trt)-OH
AZN101 Z-Asn-OH AFQ201 Fmoc-D-Gln-OH
AZQ105 Z-Gln(Trt)-OH AFQ291 Fmoc-D-Gln-OPfp
AZQ101 Z-Gln-OH UFN101 Fmoc-beta-HAsn(Trt)-OH
UFN102 Fmoc-beta-HAsn-OH
UFQ111 Fmoc-beta-HGln(Trt)-OH
UFQ101 Fmoc-beta-HGln-OH

MSDS