Fmoc-Lys(Boc)-OH [71989-26-9] HEADING_TITLE

N-alpha-Fmoc-N-epsilon-Boc-L-lysine

Other Names: Fmoc-L-Lys(Boc)-OH; Nα-Fmoc-Nε-Boc-L-lysine

Catalog # AFK105 CAS 71989-26-9
Formula C26H32N2O6 M.W. 468.5

Fmoc-Lys(Boc)-OH







Fmoc-Lys(Boc)-OH is the standard Fmoc-Lys derivative used in peptide synthesis. The Boc group is readily removed with trifluoroacetic acid (TFA) during cleavage of the peptide product from Wang resin or Rink amide resin.  Methylation or acetylation of lysine side chains in histones play important roles in DNA regulation.  AAPPTec offers side chain methylated or acetylated lysine derivatives suitably protected for for solid phase peptide synthesis.  Lysine residues also are convenient sites for attaching tags or dye labels.  AAPPTec provides Fmoc-Lys derivatives with side chain protecting groups that can be selectively removed.  The 2-Cl-Z group of Fmoc-Lys(2-Cl-Z)-OH can be removed by hydrogenolysis following peptide cleavage from the resin (Technical Bulletin 1169).  Fmoc-Lys(Dde)-OH and Fmoc-Lys(ivDde)-OH can be sidechain deprotected with hydrazine or hydroxylamine (Technical Bulletin 1182).  Fmoc-Lys(Mtt)-OH can be deprotected with mild acid (Technical Bulletin 1181) and Fmoc-Lys(Trt)-OH can be deprotected with moderate acid.  Fmoc-Lys(Aloc)-OH can be deprotected selectively under mild conditions with palladium catalyst (Technical Bulletin 1144).

Products Similar to Fmoc-Lys(Boc)-OH

Cat. # Product Cat. # Product
AFK110 Fmoc-Lys(2-Cl-Z)-OH ABK115 Boc-Lys(2-Cl-Z)-OH
AFK115 Fmoc-Lys(Ac)-OH ABK135 Boc-Lys(Ac)-OH
AFK111 Fmoc-Lys(Aloc)-OH ABK140 Boc-Lys(Boc)-OH
AFK104 Fmoc-Lys(Biotin)-OH ABK120 Boc-Lys(Fmoc)-OH
AFK135 Fmoc-Lys(Dabcyl)-OH ABK110 Boc-Lys(Z)-OH
AFK140 Fmoc-Lys(Dde)-OH ABK143 Boc-Lys(Boc)-ONp
AFK141 Fmoc-Lys(ivDde)-OH ABK125 Boc-Lys(Boc)-OSu
AFK108 Fmoc-Lys(Dnp)-OH ABK147 Boc-Lys(Z)-OSu
AFK107 Fmoc-Lys(Fmoc)-OH ABK145 Boc-Lys(Z)-pNA
AFK150 Fmoc-Lys(Boc,Me)-OH ABK101  Boc-Lys
AFK151 Fmoc-Lys(Me2)-OH HCl ABK103  Boc-Lys-OSu
AFK152 Fmoc-Lys(Me3)-OH+ Cl- DBK115  Boc-Lysinol(2-Cl-Z)
AFK125 Fmoc-Lys(Mtt)-OH DBK110  Boc-Lysinol(Z)
AFK145 Fmoc-Lys(N3)-OH ABO115  Boc-Orn(2-Cl-Z)-OH
AFK130 Fmoc-Lys(Tfa)-OH UBK110  Boc-beta-HLys(Z)-OH
AFK109 Fmoc-Lys(Trt)-OH ABO105  Boc-Orn(Fmoc)-OH
AFK106 Fmoc-Lys(Z)-OH ABO110 Boc-Orn(Z)-OH
AFK211 Fmoc-D-Lys(Aloc)-OH ABO101 Boc-Orn-OH
AFK205 Fmoc-D-Lys(Boc)-OH ABO210 Boc-D-Orn(Z)-OH
AFK240 Fmoc-D-Lys(Dde)-OH AZK102 Z-Lys(Boc)-OH
AFK241 Fmoc-D-Lys(ivDde)-OH AZK105 Z-Lys(Boc)-OH DCHA
AFK245 Fmoc-D-Lys(N3)-OH AZK103 Z-Lys(Boc,iPr)-OH
AFK195 Fmoc-Lys(Boc)-OPfp AZK104 Z-Lys(Z)-OH
AFK197 Fmoc-Lys(Fmoc)-OPfp AZK101 Z-Lys-OH
AFK295 Fmoc-D-Lys(Boc)-OPfp AZK201 Z-D-Lys-OH
AFK101 Fmoc-Lys-OH HCl UZK105 Z-beta-HLys(Boc)-OH
AFK201 Fmoc-D-Lys-OH UZK205 Z-D-beta-HLys(Boc)-OH
MFK105 Fmoc-MeLys(Boc)-OH    
DFK105 Fmoc-Lysinol(Boc)    
UFK105 Fmoc-beta-HLys(Boc)-OH    
AFO111 Fmoc-Orn(Aloc)-OH    
AFO105 Fmoc-Orn(Boc)-OH    
AFO102 Fmoc-Orn(Dde)-OH    
AFO205 Fmoc-D-Orn(Boc)-OH    
UFO130 Fmoc-Nva(N3)-OH    
UFO230 Fmoc-D-Nva(N3)-OH    
UFO111 Fmoc-Dab(Boc)-OH    
UFO112 Fmoc-Dab(Mtt)-OH    
UFK120 Fmoc-Abu(N3)-OH    
UFK220 Fmoc-D-Abu(N3)-OH    
UFO121 Fmoc-Dap(Boc)-OH    
UFO102 Fmoc-Dap(Dde)-OH    
UFO141 Fmoc-Dap(Z)-OH    
UFO101 Fmoc-Dap-OH    

MSDS