N-Methyl Amino Acid References HEADING_TITLE

N-Methyl Amino Acids in Natural Products

Sanchez LM, Lopez D, Vesely BA, Tonga GD, Gerwick WH, Kyle DE, Linington RG. J. Med. Chem. 2010, 53, 4187-97.

Hughes AB, Sleebs MM. J. Org. Chem. 2005, 70, 3079-88.

Marsh IR, Teague MBSJ. J. Org. Chem. 1997, 62, 6199-203.

Petcher TJ, Weber H, Rϋegger A. Helv. Chim. Acta 1976, 59, 1480-9.

Traber R, Kuhn M, Rϋegger A, Lichti H, Loosli RH, von Wartberg A. Helv. Chim. Acta 1977, 60, 1247-55.

N-Methyl Amino Acids Increase Proteolytic Stability

Chatterjee J, Gilon C, Kessler H. Accounts Chem. Res. 2008, DOI: 10.1021/ar8000603.

Bose PP, Chatterjee U, Hubatsch I, Artursson P, Govender T, Kruger HG, Bergh M, Johansson J, Arvidsson PI. Bioorg. Med. Chem. 2010, 18, 5896-902.

Biron E, Chatterjee J, Ovadia O, Langenegger D, Brueggen J, Hoyer D, Schmid HA, Jelinek R, Gilon C, Hoffman A, Kessler H. Angew. Chemie, Int. Ed. Eng. 2008, 47, 2595-9.

Malakoutikhan M, Teixidό M, Giralt E. J. Med. Chem. 2008, 51, 4881-9.

Cody WL, He JX, Reily MD, Haleen SJ, Walker DM, Reyner EL, Stewart BH, Doherty AM. J. Med. Chem. 1997, 40, 2228-40.

N-Methyl Amino Acids Increase Selectivity

Doedens L, Opperer F, Cai M, Beck JG, Dedek M, Palmer E, Hruby VJ, Kessler H. J. Am. Chem. Soc. 2010, 132, 8115-28.

Chatterjee J, Ovadia O, Zahn G, Marinelli L, Hoffman A, Gilon C, Kessler H. J. Med. Chem. 2007, 50, 5878-81.

Vaudry SBD, Sgalas-Milazzo I, Guilhaudis L, Couvineau A, Laburthe M, Vaudry H., Fournier A. J. Med. Chem. 2009, 52, 3308-16.

N-Methyl Amino Acid Peptides Cross the Blood-Brain Barrier

Malakoutikah M, Prades R, Teixidό M, Giralt E. J. Med. Chem. 2010, 53, 2354-63.

Malakoutikhan M, Teixidό M, Giralt E. J. Med. Chem. 2008, 51, 4881-9.