Boc-D-Amino Acids HEADING_TITLE

Boc-D-amino acids are not as frequently used as the corresponding L-isomers because D-amino acids do not occur in the proteins and peptides produced by higher organisms. However D-amino acids are often found in the peptidoglycans contained in the cell membranes of many microbes. Many natural and synthetic peptides containing D-amino acids possess strong antimicrobial properties.

Boc-D-amino acids are often used in drug development studies. Beside antimicrobial properties, introducing D-amino acids into a synthetic peptide can make the peptide less susceptible to enzymatic degradation and improves its drug characteristics. For example D-amino acids are often used to increase the stability of a peptide to proteases. D-amino acids can be incorporated in place of the natural L-amino acids, either at a specific position, or throughout the whole peptide.

Cyclic analogs of small bioactive peptides are being studied as potential drug targets. These small cyclic peptides often contain at least one D-amino acid. Including a D-amino acid in the linear precursor peptide allows efficient cyclization.

Boc-D-Amino Acids are greater than 99% pure and competitively priced.

AAPPTec offers a wide selection of very high purity, competitively priced Boc-D-Amino Acids. All Boc-D-amino acids are available in kilogram or bulk quantities. E-mail AAPPTec at sales@aapptec.com  for a bulk quotation or use the On-Line Quotation Request.

A Few of the High Quality Boc-D-Amino Acids Available from AAPPTec:

Boc-D-Alanine

Boc-D-Arginine(Tos)

Boc-D-Aspartic Acid(OBzl)

Boc-D-Asparagine

Boc-D-Cysteine(Trt)

Boc-D-Glutamic Acid(OBzl)

Boc-D-Glutamine(Trt)

Boc-D-Histidine(DNP)

Boc-D-Histidine(Tos)

Boc-D-Isoleucine

Boc-D-Leucine

Boc-D-Lysine(Fmoc)

Boc-D-Lysine(2-Cl-Z)

Boc-D-Methionine

Boc-D-Phenylalanine

Boc-D-Proline

Boc-D-Serine(Bzl)

Boc-D-Threonine(Bzl)

Boc-D-Tryptophan

Boc-D-Tyrosine(2-Br-Z)

Boc-D-Valine

 

general Boc-D-Amino acid