Fmoc-His(Trt)-OH [109425-51-6] HEADING_TITLE


Other Names: Fmoc-L-His(Trt)-OH; Nα-Fmoc-Nτ-triphenylmethyl-L-histidine

Catalog # AFH105 CAS 109425-51-6
Formula C40H33N3O4 M.W. 619.7









Fmoc-His(Trt)-OH is the histidine derivative most commonly utilized in peptide synthesis by Fmoc chemistry.  The Trt group is easily removed with acid, but the trityl cation may reattach at nucleophilic sites in the resin. Using cleavae cocktails containing triisopropylsilane (TIS) or ethane dithiol will minimize this side reaction.

Products Similar to Fmoc-His(Trt)-OH

Cat. # Product Cat. # Product
AFH115 Fmoc-His(Fmoc)-OH ABH101 Boc-His-OH
AFH110 Fmoc-His(Mmt)-OH ABH126 Boc-His(Boc)-OH
AFH195 Fmoc-His(Trt)-OPfp ABF130 Boc-His(Bom)-OH
AFH205 Fmoc-D-His(Trt)-OH ABF110 Boc-His(Dnp)-OH IPA
MFH105 Fmoc-MeHis(Trt)-OH ABF115 Boc-His(Tos)-OH
UFH121 Fmoc-Ala(4-Thiazolyl)-OH ABH135 Boc-His(Trt)-OH
UFH221 Fmoc-D-Ala(4-Thiazolyl)-OH ABH140 Boc-His(Z)-OH
AZH101 Z-His-OH ABH210 Boc-D-His(Dnp)-OH IPA
AZH102 Z-His(Dnp)-OH ABH230 Boc-D-His(Bom)-OH
AZH201 Z-D-His-OH ABH215 Boc-D-His(Tos)-OH

DBH105 Boc-Histidinol(Tos)
UBH121 Boc-Ala(4-Thiazolyl)-OH
UBH221 Boc-D-Ala(4-Thiazolyl)-OH