Titan 357 Description
The Titan 357 synthesizer is a powerful tool for drug discovery. It serves as three automated synthesizers in one. As a parallel synthesizer it prepares up to 36 peptides simultaneously. It is also a 550 mL scale-up synthesizer, as well as a split-and-combine synthesizer for preparing combinatorial peptide libraries. It can prepare split-and-combine libraries containing millions of compounds for high throughput screening and lead discovery. In lead development and optimization studies, the Titan 357 can prepare up to 36 peptides simultaneously. Finally, it can prepare single peptides in multi-gram quantities for initial in vivo testing.
The Titan 357 utilizes the split-and-combine protocols developed by Furka, Lam, Hruby and Houghton to automatically generate combinatorial libraries containing thousands to millions of compounds. Designing custom libraries is simple with its versatile, easy-to-use software. The user can create completely randomized peptide libraries or libraries of peptides with only a few randomized positions within the sequence.
As a parallel synthesizer, the Titan 357 can prepare up to 36 separate peptides simultaneously. Gentle but efficient vortex mixing thoroughly mixes the resin in the (36) 10 mL reaction units of the reactor assembly.
The Titan 357 can prepare multi-gram quantities of peptides utilizing either Boc or Fmoc protocols.
Key Features
- Program-Controlled Variable Speed Vortex Mixer
- Inert Atmosphere
- 36 Well Reactor Capacity
- Temperature Controlled Amino Acid Vessels
- Easy-to-Use Windows Software
- Diluter/Syringe Dispensing System with Micro-liter Accuracy
Size
W: 31.5 inches (80 cm) without computer
H: 25 inches (63.5 cm)
D: 22.75 inches (57.5 cm)
Weight: 220 lbs (100 kg) without computer
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